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Understanding NRC License Amendments for Sealed Sources and Devices

By QSA Global Regulatory Affairs | Apr 27, 2026 |

If your organization needs to add a sealed source, source holder or assembly, source wire, or device to an existing U.S. Nuclear Regulatory Commission (NRC) materials license, an amendment request using NRC Form 313 (Application for Materials License) is required. NRC Form 313 is the official mechanism used by the NRC to review and approve changes to a radioactive materials license, including the authorization of new sources or registered devices. 

All sources and devices added through an amendment must be properly evaluated, and identified by the correct manufacturer, model number and Sealed Source and Device Registration (SSDR), if applicable. Submitting a complete and accurate amendment request helps ensure regulatory compliance and avoid licensing delays.

 Agreement States

Agreement States are authorized by the U.S. Nuclear Regulatory Commission (NRC) to license and inspect the use of certain radioactive materials within their borders. Applicants seeking to possess or use licensed material in an Agreement State (other than federal agencies or federally recognized Indian tribes) must apply directly to the appropriate state regulatory authority, not the NRC. Select your state below to access your local regulator’s website for guidance

Alabama  Kansas  New Hampshire South Carolina  
Arizona  Kentucky New Jersey Tennessee  
Arkansas  Louisiana New Mexico Texas  
California  Maine New York  Utah
Colorado  Maryland North Carolina Vermont
Connecticut  Massachusetts North Dakota  Virginia  
Florida  Minnesota Ohio Washington  
Georgia  Mississippi Oklahoma  Wisconsin
Illinois  Nebraska Oregon  Wyoming
Iowa  Nevada Pennsylvania    

Non-Agreement States and Territories

In Non‑Agreement States, the U.S. Nuclear Regulatory Commission (NRC) retains authority for licensing and inspection of byproduct, source, and special nuclear materials. Applicants wishing to possess or use licensed radioactive material in a Non‑Agreement State must apply directly to the NRC. State agencies do not issue licenses for NRC‑regulated materials in these jurisdictions. Refer to the NRC for application requirements and regulatory guidance.

Alaska Indiana Puerto Rico U.S. Virgin Island
Delaware Michigan South Dakota Washington, DC
Hawaii Missouri U.S. Pacific Territories West Virginia  
 Idaho Montana      

U.S. NRC Regional Contacts

The U.S. Nuclear Regulatory Commission (NRC) maintains regional offices across the United States to support its regulatory mission at the local and regional level. These offices are responsible for conducting inspections, overseeing licensee performance, enforcing NRC regulations, and serving as a point of contact for licensees, Agreement States, and the public.

Licensees and applicants may need to work with their assigned NRC regional office for activities such as routine inspections, compliance and enforcement matters, incident response, and regulatory guidance. NRC regional offices help ensure consistent application of NRC requirements while maintaining oversight to protect public health, safety, and the environment within each region’s jurisdiction.